糖尿病视网膜病变中医证候分布规律及症状相关性研究(1)
[摘要]挖掘糖尿病視网膜病变的中医证候分布规律及症状之间的相关性。以中国知网全文数据库(CNKI)、万方数据知识服务平台、维普网、中国生物医学文献数据库(CBM)、PubMed中公开发表的文献为基础，运用SPSS 200与IBM SPSS Modeler 141软件为工具，通过频数统计分析症状、病位、舌象、脉象、证候分型的分布情况，关联规则算法探索糖尿病视网膜病变的潜在症状组合的基本规律。共检索出560篇文献，符合纳入与排除标准的有240篇，其中中医证候62个，涉及病例9 820例，症状201条，舌象29种，脉象36种，病位分布肝、肾居于前两位，高频症状关联规则分析挖掘出潜在症状群15组，高频症状与舌象、脉象潜在症状组合3组。研究表明糖尿病视网膜病变的发病以气阴两虚证最多，病位与肝肾关系密切，高频症状与舌象、脉象、潜在症状组合可以作为诊断时的主症出现，为深入研究本病的PRO量表的流行病学调查提供文献参考，亦可以直接作为主症而加大这些症状出现时的权重，还可以作为中医证候诊断量表的备选条目池，进而为糖尿病视网膜病变中医症状条目库的构建和优化奠定基础。
, 百拇医药
[关键词]糖尿病视网膜病变； 证候分布； 症状相关性； 关联规则； 症状组合
[Abstract]To investigate the distribution of traditional Chinese medicine (TCM) Syndromes of diabetic retinopathy and explore the correlation between various symptoms Based on the literature in databases of China Journal Fulltext Database (CNKI)， Wanfang database， VIP network， China biomedical literature database (CBM) and PubMed， SPSS 200 and IBM SPSS Modeler 141 software were used to analyze the location of disease， symptoms， tongue and pulse， and syndrome type distribution through frequency statistics In addition， association rule algorithm was used to explore the basic rules for underlying symptoms combinations of diabetic retinopathy A total of 560 articles were retrieved， and a total of 240 articles met the inclusion and exclusion criteria In these documents， 62 types of TCM syndromes were found， involving 9 820 cases， 201 symptoms， 29 tongue conditions， and 36 pulses conditions； the first two locations for the disease were liver and kidney Then the association rule analysis of high frequency symptoms was used to dig out 15 groups of latent syndrome， and 3 underlying symptom combinations among high frequency symptoms， tongue conditions and pulse conditions The results of the study showed that Qi and yin deficiency was most common for the diabetic retinopathy， and the location of the disease was closely related to liver and kidney In addition， these highfrequency symptoms and tongue conditions， pulse conditions， and underlying symptom combinations can occur as main symptoms at diagnosis， providing reference for us to study the epidemiology of PRO scale of the disease They can also increase the weight of these symptoms directly as the main symptoms， which can be also used as an alternative entry pool for TCM syndrome diagnostic scale， laying foundation for the construction and optimization of TCM symptom database of diabetic retinopathy
[Key words]diabetic retinopathy； distribution of syndrome； correlation between symptoms； association rules； combination of symptoms, 百拇医药(赵艳青 李青松 项敏泓 张薇 张兴儒)
, 百拇医药
[关键词]糖尿病视网膜病变； 证候分布； 症状相关性； 关联规则； 症状组合
[Abstract]To investigate the distribution of traditional Chinese medicine (TCM) Syndromes of diabetic retinopathy and explore the correlation between various symptoms Based on the literature in databases of China Journal Fulltext Database (CNKI)， Wanfang database， VIP network， China biomedical literature database (CBM) and PubMed， SPSS 200 and IBM SPSS Modeler 141 software were used to analyze the location of disease， symptoms， tongue and pulse， and syndrome type distribution through frequency statistics In addition， association rule algorithm was used to explore the basic rules for underlying symptoms combinations of diabetic retinopathy A total of 560 articles were retrieved， and a total of 240 articles met the inclusion and exclusion criteria In these documents， 62 types of TCM syndromes were found， involving 9 820 cases， 201 symptoms， 29 tongue conditions， and 36 pulses conditions； the first two locations for the disease were liver and kidney Then the association rule analysis of high frequency symptoms was used to dig out 15 groups of latent syndrome， and 3 underlying symptom combinations among high frequency symptoms， tongue conditions and pulse conditions The results of the study showed that Qi and yin deficiency was most common for the diabetic retinopathy， and the location of the disease was closely related to liver and kidney In addition， these highfrequency symptoms and tongue conditions， pulse conditions， and underlying symptom combinations can occur as main symptoms at diagnosis， providing reference for us to study the epidemiology of PRO scale of the disease They can also increase the weight of these symptoms directly as the main symptoms， which can be also used as an alternative entry pool for TCM syndrome diagnostic scale， laying foundation for the construction and optimization of TCM symptom database of diabetic retinopathy
[Key words]diabetic retinopathy； distribution of syndrome； correlation between symptoms； association rules； combination of symptoms, 百拇医药(赵艳青 李青松 项敏泓 张薇 张兴儒)